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Combined transcatheter mitral and tricuspid edge-to-edge repair or tricuspid edge-to-edge repair alone in moderate mitral regurgitation: a propensity-matched analysis.

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Related Experiment Video

Updated: Jul 13, 2025

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools
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[T-TEER: description of a development process].

Philipp M Doldi1,2, Lukas Stolz3,4, Ludwig T Weckbach3,4

  • 1Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Marchioninistr. 15, 81377, München, Deutschland. philipp.doldi@med.uni-muenchen.de.

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|October 13, 2023
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Summary
This summary is machine-generated.

Tricuspid valve regurgitation (TR) is a significant condition. New interventional treatments offer a safe and effective option for patients, improving heart failure symptoms and quality of life.

Keywords:
Edge-to-edge procedureHeart failureHospitalizationImagingTricuspid valve insufficiency

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Area of Science:

  • Cardiology
  • Interventional Cardiology

Context:

  • Tricuspid valve regurgitation (TR) is increasingly recognized as a significant independent condition, not just a consequence of left heart disease.
  • Severe TR can cause right ventricular volume overload, annular dilatation, and lead to heart failure, reduced quality of life, and mortality.
  • Traditional surgical options for TR carry high risks, leaving many patients inoperable.

Purpose:

  • To review the current landscape of interventional treatments for tricuspid valve regurgitation (TR).
  • To highlight the safety and efficacy of emerging transcatheter edge-to-edge repair (TEER) procedures.
  • To emphasize the role of cardiovascular imaging in patient selection and procedural timing.

Summary:

  • Transcatheter edge-to-edge repair (TEER) procedures, such as those using the TriClip™ or PASCAL™ systems, are safe and effective for treating TR.
  • These interventions have demonstrated promising results in reducing TR severity, alleviating heart failure symptoms, and improving patient quality of life.
  • Ongoing randomized studies are evaluating the long-term impact of TEER on mortality and hospitalization rates.

Impact:

  • Interventional TR treatments represent a major advancement, offering a viable option for previously inoperable patients.
  • Improved management of TR can lead to reduced hospitalizations for heart failure and enhanced patient survival.
  • Personalized patient selection and precise procedural timing, guided by advanced imaging, are key to optimizing outcomes.