Related Experiment Video
Updated: Jul 13, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Stenotrophomonas maltophilia endophthalmitis following keratoplasty
Bilge Tarım1, Mücella Arıkan Yorgun2, Birsen Özdem3
1Department of Ophthalmology, University of Health Sciences, Ankara Bilkent City Hospital, Ankara, Turkey. bilge_basciftci@hotmail.com.
Abstract:
Endophthalmitis is among the most sight-threatening infections in ophthalmology practice. Many microorganisms causing endophthalmitis have been reported. Stenotrophomonas maltophilia is among the rare causes of endophthalmitis and has been reported after cataract surgery, intravitreal injections and ocular trauma. We report a case of S. maltophilia endophthalmitis after keratoplasty, which is a rare entity, in a 63-year-old female patient.
Insights
Stenotrophomonas maltophilia is a rare cause of endophthalmitis. This case highlights a rare instance of S. maltophilia endophthalmitis occurring after a keratoplasty procedure.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endophthalmitis is a severe intraocular infection posing a significant threat to vision.
- Various microorganisms can cause endophthalmitis, with some being more common than others.
- Stenotrophomonas maltophilia is an opportunistic pathogen occasionally implicated in endophthalmitis, typically following procedures like cataract surgery, intravitreal injections, or ocular trauma.
Purpose of the Study:
- To report a rare case of endophthalmitis caused by Stenotrophomonas maltophilia.
- To document this infection in the context of a specific ocular procedure: keratoplasty.
- To contribute to the understanding of rare microbial causes of post-keratoplasty endophthalmitis.
Main Methods:
- Case report of a 63-year-old female patient.
- Clinical presentation and microbiological investigation of endophthalmitis.
- Review of literature regarding Stenotrophomonas maltophilia endophthalmitis, particularly post-keratoplasty.
Main Results:
- The patient developed endophthalmitis following a keratoplasty procedure.
- The causative agent was identified as Stenotrophomonas maltophilia.
- This represents a rare occurrence of S. maltophilia-induced endophthalmitis after corneal transplantation.
Conclusions:
- Stenotrophomonas maltophilia can be a cause of endophthalmitis, even after keratoplasty.
- Ophthalmologists should consider a broad range of microorganisms, including rare pathogens like S. maltophilia, in cases of post-keratoplasty endophthalmitis.
- Further investigation into risk factors and management strategies for S. maltophilia endophthalmitis post-keratoplasty may be warranted.

