Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

42
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
42
Dissociative Disorders01:27

Dissociative Disorders

134
Dissociative disorders represent complex psychological conditions characterized by disruptions in consciousness, memory, identity, or perception. These disruptions cause individuals to experience a disconnection from their thoughts, emotions, and memories. The phenomenon is not merely an occasional lapse in attention but a profound alteration in mental functioning that can severely impact daily life.
Dissociative Fugue
A hallmark feature of dissociative disorders is the dissociative fugue...
134
Traumatic Memory01:20

Traumatic Memory

95
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
95
Dissociative Identity Disorder01:30

Dissociative Identity Disorder

135
Dissociative Identity Disorder (DID), previously termed multiple personality disorder, is a complex psychological condition characterized by the presence of two or more distinct identities or personality states. Each identity exhibits unique patterns of behavior, voice, and mannerisms and may possess separate memories and emotional responses. The alternating control between identities can result in memory gaps and challenges in recalling daily activities, often exacerbating the individual's...
135
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

142
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
142

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidences of Concussion in the United States: A Review of Health Insurance Claims.

Brain sciences·2026
Same author

The Effect of Performance Training on Sideline Concussion Assessments in Adolescent Athletes: A Pilot Investigation.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine·2026
Same author

CARE-ing for concussions: Development of the Calgary Adapted aRm Ergometer (CARE) exertion test: A physiological alternative to the Calgary Concussion Cycle Test.

Experimental physiology·2026
Same author

Sex Differences in the Treatment Effect of Targeted Heart Rate Aerobic Exercise in Adolescents with Acute Sport-Related Concussion.

Journal of neurotrauma·2026
Same author

Radiographic Risk Factors for Scapular Stress Fractures After Reverse Total Shoulder Arthroplasty: A Case-Control Study.

The Journal of the American Academy of Orthopaedic Surgeons·2026
Same author

Brief Report: The Effect of Environmental Distractions on Preseason SCAT6 Cognitive Performance.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine·2026
Same journal

A Systematic Review and Meta-Analysis of Randomized Controlled Trials of Epidural Regenerative Medicine Therapies in Managing Spinal Pain.

Current pain and headache reports·2026
Same journal

Artificial Intelligence in Neuropathic Pain: From Mechanisms to Neuromodulation and Regenerative Strategies.

Current pain and headache reports·2026
Same journal

Proposed Conditions for Pain Reprocessing Therapy Readiness: Beyond Phenotyping Neuroplastic Pain.

Current pain and headache reports·2026
Same journal

Treatment of Headache in Children and Adolescents with POTS.

Current pain and headache reports·2026
Same journal

Pediatric Headache in the Age of Social Media: A Topical Review.

Current pain and headache reports·2026
Same journal

Radiopharmaceuticals for the Treatment of Chronic Cancer Pain.

Current pain and headache reports·2026
See all related articles

Related Experiment Video

Updated: Jul 13, 2025

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
11:32

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

12.8K

Does Physiologic Post-Concussion Disorder Cause Persistent Post-Traumatic Headache?

Jacob I McPherson1, Muhammad S Z Nazir2, Barry S Willer3

  • 1Department of Rehabilitation Science, School of Public Health and Health Professions, State University of New York at Buffalo, 534 Kimball Tower, Buffalo, NY, 14214, USA. jim6@buffalo.edu.

Current Pain and Headache Reports
|October 13, 2023
PubMed
Summary
This summary is machine-generated.

Physiologic post-concussion disorder (PCD) may cause persistent post-traumatic headaches (PPTH) due to metabolic and autonomic nervous system issues. Further research is needed to prevent PPTH in these patients.

Keywords:
ConcussionHeadachePhysiologic post-concussion disorderPost-traumatic headache

More Related Videos

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
07:21

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

3.2K
An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
07:02

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System

Published on: January 12, 2011

15.9K

Related Experiment Videos

Last Updated: Jul 13, 2025

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
11:32

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

12.8K
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
07:21

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

3.2K
An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
07:02

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System

Published on: January 12, 2011

15.9K

Area of Science:

  • Neuroscience
  • Sports Medicine
  • Neurology

Background:

  • Concussion can lead to various post-concussion disorders (PCD).
  • Headache is the most common symptom following a concussion.
  • A classification system categorizes PCD into physiologic, vestibulo-ocular, cervicogenic, and mood/cognition subtypes.

Purpose of the Study:

  • To review the literature on physiologic post-concussion disorder (PCD).
  • To explore the relationship between physiologic PCD and persistent post-traumatic headaches (PPTH).

Main Methods:

  • Literature review of studies on concussion, PCD, and PPTH.
  • Analysis of proposed mechanisms linking physiologic PCD to headache development.

Main Results:

  • Headaches are a primary symptom after concussion.
  • Physiologic PCD is hypothesized to stem from cellular metabolism abnormalities, neuroinflammation, and autonomic nervous system (ANS) dysfunction.
  • These physiological changes are associated with the development of migraine-like and neuralgia-related PPTH.

Conclusions:

  • Physiologic PCD is a potential cause of persistent post-traumatic headaches (PPTH) after concussion.
  • Abnormal cellular metabolism, neuroinflammation, and ANS dysfunction in physiologic PCD may contribute to PPTH.
  • Future research should investigate strategies to prevent PPTH in individuals with physiologic PCD.