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Cytokine profiles in COVID-19 patients undergoing adjunct ozone therapy: some comments

Salvatore Chirumbolo1, Sergio Pandolfi2, Marianno Franzini2

  • 1Department of Engineering for Innovation Medicine, University of Verona, Strada Le Grazie 8, 37134, Verona, Italy. salvatore.chirumbolo@univr.it.

Inflammopharmacology
|October 13, 2023
PubMed

Insights

Ozone therapy may help moderate COVID-19 patients by improving antioxidant status and cytokine profiles. Further research is needed to confirm its benefits as a medicinal supplement.

Area of Science:

  • Immunology
  • Oxidative Stress Research
  • COVID-19 Therapeutics

Background:

  • COVID-19 is associated with significant immune dysregulation, including altered cytokine profiles and increased oxidative stress.
  • Antioxidant status plays a crucial role in the severity of COVID-19.
  • Ozone therapy is being investigated for its potential immunomodulatory and antioxidant effects.

Purpose of the Study:

  • To evaluate the impact of ozone therapy on cytokine profiles and antioxidant status in patients with moderate and severe COVID-19.
  • To assess ozone therapy as a potential medicinal supplement for COVID-19 management.

Main Methods:

  • The study involved patients with moderate and severe COVID-19.
  • Cytokine levels and antioxidant markers were measured.
  • The effects of ozone therapy as a supplement were analyzed.

Main Results:

  • Ozone therapy demonstrated a positive impact on the cytokine profile in moderate COVID-19 patients.
  • Improvements in antioxidant status were observed in patients receiving ozone therapy.
  • The study provides preliminary evidence for ozone therapy's potential benefits.

Conclusions:

  • Ozone therapy may serve as a beneficial medicinal supplement for managing COVID-19, particularly in moderate cases.
  • Further clinical trials are warranted to establish optimal protocols and confirm efficacy.
  • The findings contribute to understanding the therapeutic potential of ozone in viral infections.

Keywords:
COVID-19OzoneOzone therapy

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