Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discovery of (2<i>R</i>,4<i>R</i>)-4-((<i>S</i>)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.

Journal of medicinal chemistry·2024
Same author

Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.

Journal of medicinal chemistry·2024
Same author

CRISPR-Cas12a-regulated DNA adsorption on MoS<sub>2</sub> quantum dots: Enhanced enzyme mimics for sensitive colorimetric detection of human monkeypox virus and human papillomavirus DNA.

Talanta·2024
Same author

3D printing incorporating gold nanozymes with mesenchymal stem cell-derived hepatic spheroids for acute liver failure treatment.

Biomaterials·2024
Same author

Subglottic airway injury during fiberscope-monitored intubation with a supraglottic airway device: A randomized controlled comparison of three tracheal tubes.

Chinese medical journal·2024
Same author

Effects of filling substrates on remediation performance and sulfur transformation of sulfate reducing packed-bed bioreactors treating acid mine drainage.

Journal of environmental management·2024

Related Experiment Video

Updated: Jul 13, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.6K

Key steps for improving bacterial SERS signals in complex samples: Separation, recognition, detection, and analysis.

Maomei Xie1, Yiting Zhu1, Zhiyao Li1

  • 1College of Pharmaceutical Engineering of Traditional Chinese Medicine (TCM), Tianjin University of TCM, Tianjin, 301617, China.

Talanta
|October 13, 2023
PubMed
Summary

Surface-enhanced Raman spectroscopy (SERS) offers sensitive detection of pathogenic bacteria. This review details methods to improve SERS analysis in complex samples, addressing challenges for broader application.

Keywords:
ChemometricsComplex samplesPathogenic bacteriaRapid detectionSurface-enhanced Raman spectroscopy (SERS)

More Related Videos

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.4K
A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.4K

Related Experiment Videos

Last Updated: Jul 13, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.6K
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.4K
A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.4K

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Microbiology

Background:

  • Pathogenic bacteria detection is critical for environmental, food, and medical fields.
  • Surface-enhanced Raman spectroscopy (SERS) provides sensitive, selective, and rapid bacterial detection.
  • SERS faces challenges in complex matrices, including interference, similar bacteria differentiation, and data complexity.

Purpose of the Study:

  • To review and summarize key steps for enhancing bacterial SERS signals in complex samples.
  • To highlight principles, roles, and interconnectivity of separation, recognition, detection, and analysis in SERS.
  • To discuss current challenges and future trends in SERS for bacterial detection.

Main Methods:

  • Review of existing literature on SERS techniques for bacterial analysis.
  • Analysis of front-end (data acquisition) and back-end (data processing) strategies.
  • Focus on improving signal-to-noise ratio and specificity in complex matrices.

Main Results:

  • Identification of crucial steps: separation, recognition, detection, and analysis for effective SERS.
  • Demonstration of technologies assisting SERS in overcoming matrix interference and data complexity.
  • Overview of advancements in SERS for pathogenic bacteria detection.

Conclusions:

  • SERS is a powerful tool for pathogenic bacteria detection, but requires optimized sample preparation and data analysis.
  • Addressing challenges in complex matrices is key to unlocking the full potential of SERS.
  • Further research into integrated SERS approaches will facilitate practical applications in diverse fields.