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Updated: Jul 13, 2025

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
Published on: January 16, 2016
Optimization of escape kinetics by reflecting and resetting
Karol Capała1,2, Bartłomiej Dybiec2
1Personal Health Data Science Group, Sano-Centre for Computational Personalised Medicine, Czarnowiejska 36, 30-054 Kraków, Poland.
Abstract:
Stochastic restarting is a strategy of starting anew. Incorporation of the resetting to the random walks can result in a decrease in the mean first passage time due to the ability to limit unfavorably meandering, sub-optimal trajectories. In this paper, we examine how stochastic resetting influences escape dynamics from the (-∞,1) interval in the presence of the single-well power-law |x|κ potentials with κ>0. Examination of the mean first passage time is complemented by the analysis of the coefficient of variation, which provides a robust and reliable indicator assessing the efficiency of stochastic resetting. The restrictive nature of resetting is compared to placing a reflective boundary in the system at hand. In particular, for each potential, the position of the reflecting barrier giving the same mean first passage time as the optimal resetting rate is determined. Finally, in addition to reflecting, we compare the effectiveness of other resetting strategies with respect to optimization of the mean first passage time.
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