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Age- and glaucoma-induced changes to the ocular glymphatic system

Xiaowei Wang1, Christine Delle2, Weiguo Peng1

  • 1Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, Rochester, NY 14642, USA.

Neurobiology of Disease
|October 13, 2023
PubMed
Summary

Aging impairs ocular glymphatic fluid transport, affecting waste removal and light responses. Glaucoma, however, pathologically increases this transport, suggesting distinct therapeutic targets for optic nerve health.

Keywords:
Enlarged perivascular spaceOcular agingOcular glymphatic systemglaucoma

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