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Updated: Jul 13, 2025

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Post-Ureteroscopic Lesion Scale to determine ureteral wall damage, not so easy to employ
R Polo1, À Canós-Nebot2, J P Caballero-Romeu2
1Servicio de Urología, Hospital Marina Baixa, Denia, Valencia, Spain.
Objective:
To analyze the level of agreement of the Post-Ureteroscopy Lesion Scale (PULS) and the consequences on its application in clinical practice with more reliable statistical data than the one used in the original work.
Methods:
14 URS and 14 micro-URS were performed in 14 female porcine model. All the procedures were video recorded and an anatomopathological analysis was performed in each ureter. Sixteen urologists (9 endourologists and 7 general urologists) and 4 residents evaluated the ureteral lesions according to the PULS, with degrees 0, 1 and ≥2. The agreement was calculated with percentages, Kendall's W coefficient and the indicators Fleiss' Kappa and Krippendorff's Alpha, while the inter-rater agreement was calculated with Spearman's correlation and Cohen's Kappa.
Results:
The percent of agreement was 11.1%. The coefficients were likewise classified as low or very low, with the greatest agreement found among the inexperienced. Also, 50% of the raters did not agree with the rest.
Conclusions:
The low inter-rater agreement, the specificity of the PULS and the clinical-pathological correlation suggests that this scale is not simple, and probably has a long learning curve.
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