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Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...

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Related Experiment Video

Updated: Jun 17, 2026

A Spine Robotic-Assisted Navigation System for Pedicle Screw Placement
06:24

A Spine Robotic-Assisted Navigation System for Pedicle Screw Placement

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Advances and Evolving Challenges in Spinal Deformity Surgery.

Ruchit V Patel1,2, Alexander G Yearley1,2, Hannah Isaac1

  • 1Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA 02115, USA.

Journal of Clinical Medicine
|October 14, 2023
PubMed
Summary

Surgical correction for adult spinal deformity (ASD) has advanced with new techniques and technologies. However, challenges in patient selection and surgical complications still impact outcomes, requiring further validation of minimally invasive approaches.

Keywords:
minimally invasive surgeryoperative challengesspinal deformitysurgical approaches

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Area of Science:

  • Spine surgery
  • Orthopedic surgery
  • Deformity correction

Background:

  • Adult spinal deformity (ASD) requires surgical intervention.
  • Spinal surgical techniques have evolved significantly.
  • Characterizing advancements and barriers in ASD correction is crucial.

Purpose of the Study:

  • To review developments in surgical correction for adult spinal deformity (ASD).
  • To identify barriers impacting clinical outcomes in ASD surgery.
  • To examine patient and clinician perspectives on ASD surgical challenges.

Main Methods:

  • Literature review of PubMed, Embase, Web of Science, and Google Scholar.
  • Analysis of ASD surgical procedures across pre-, intra-, and post-operative phases.
  • Examination of advances and challenges in ASD correction.

Main Results:

  • Radiographic parameters and 3D modeling aid surgical planning.
  • Minimally invasive, targeted, and staged procedures enhance surgical approaches.
  • Improvements in osteotomy, navigation, and hardware increase patient safety.
  • Challenges include patient selection variability, undercorrection, and complications like infection and hardware failure.
  • Clinical validation for minimally invasive approaches is needed.

Conclusions:

  • Surgical solutions are needed to resolve symptoms of the growing prevalence of ASD.
  • Computational and imaging advances are essential for comprehensive ASD treatment plans.