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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
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Respiratory failure in systemic sclerosis
Joaquim Ivo Vasques Dantas Landim1, Andre Silva Franco2, Percival Degrava Sampaio-Barros2
1Division of Rheumatology, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, 3O. Andar, Cerqueira César, Sao Paulo, SP, CEP: 01246-903, Brazil. joaquimivovasques@gmail.com.
Rheumatology International
|October 14, 2023
Summary
Systemic sclerosis (SSc) is a challenging diagnosis, especially with respiratory failure. Early SSc diagnosis and treatment of complications like scleroderma renal crisis (SRC) are crucial for patient recovery.
Area of Science:
- Rheumatology
- Pulmonology
- Nephrology
Background:
- Systemic sclerosis (SSc) presents diagnostic challenges, particularly when complicated by respiratory failure.
- The COVID-19 pandemic further complicates the diagnosis of SSc-related respiratory issues.
Observation:
- A 26-year-old female with previously undiagnosed SSc presented with acute respiratory failure requiring intubation.
- Clinical evaluation revealed skin thickening, kidney failure, thrombocytopenia, microangiopathic anemia, and a positive antinuclear antibody test.
Findings:
- The patient was diagnosed with SSc complicated by scleroderma renal crisis (SRC).
- Treatment included hemodialysis, an angiotensin-converting enzyme inhibitor, and cyclophosphamide.
Implications:
- Prompt diagnosis and multi-faceted treatment are vital for managing SSc and its severe complications like SRC.
- This case highlights the importance of considering SSc in young patients with unexplained respiratory failure and renal involvement.
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