Consistent representation via contrastive learning for skin lesion diagnosis
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Updated: Jul 13, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Zizhou Wang1, Lei Zhang2, Xin Shu2
1College of Computer Science, Sichuan University, Chengdu 610065, China; Institute of High Performance Computing, Agency for Science, Technology and Research (A*STAR), Singapore 138632, Singapore.
Background:
Skin lesions are a prevalent ailment, with melanoma emerging as a particularly perilous variant. Encouragingly, artificial intelligence displays promising potential in early detection, yet its integration within clinical contexts, particularly involving multi-modal data, presents challenges. While multi-modal approaches enhance diagnostic efficacy, the influence of modal bias is often disregarded.
Methods:
In this investigation, a multi-modal feature learning technique termed "Contrast-based Consistent Representation Disentanglement" for dermatological diagnosis is introduced. This approach employs adversarial domain adaptation to disentangle features from distinct modalities, fostering a shared representation. Furthermore, a contrastive learning strategy is devised to incentivize the model to preserve uniformity in common lesion attributes across modalities. Emphasizing the learning of a uniform representation among models, this approach circumvents reliance on supplementary data.
Results:
Assessment of the proposed technique on a 7-point criteria evaluation dataset yields an average accuracy of 76.1% for multi-classification tasks, surpassing researched state-of-the-art methods. The approach tackles modal bias, enabling the acquisition of a consistent representation of common lesion appearances across diverse modalities, which transcends modality boundaries. This study underscores the latent potential of multi-modal feature learning in dermatological diagnosis.
Conclusion:
In summation, a multi-modal feature learning strategy is posited for dermatological diagnosis. This approach outperforms other state-of-the-art methods, underscoring its capacity to enhance diagnostic precision for skin lesions.
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