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Minimal clinically important differences on the DyNaChron questionnaire after surgery.

J Houdu1, R Jankowski1, R Renkes1

  • 1Service d'ORL et chirurgie cervico-faciale, CHRU de Nancy, hôpitaux de Brabois, allée du Morvan, 54500 Vandœuvre-lès-Nancy, France.

European Annals of Otorhinolaryngology, Head and Neck Diseases
|October 14, 2023
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Summary
This summary is machine-generated.

Minimal clinically important differences (MCIDs) were determined for the DyNaChron questionnaire in chronic rhinosinusitis patients. These values help assess treatment effectiveness for nasal obstruction, rhinorrhea, and olfaction quality of life.

Keywords:
Chronic nasal dysfunctionDyNaChronHealth-related quality of lifeNasal polyposisSNOT-22Septal deviation

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Area of Science:

  • Otolaryngology
  • Quality of Life Research

Background:

  • Minimal clinically important differences (MCIDs) represent the smallest score change indicating patient-relevant treatment benefit.
  • MCIDs are crucial for evaluating treatment efficacy in quality-of-life assessments.
  • MCIDs for the DyNaChron chronic rhinosinusitis questionnaire have not been previously established.

Purpose of the Study:

  • To establish the minimal clinically important differences (MCIDs) for the DyNaChron quality-of-life questionnaire.
  • To provide benchmarks for assessing treatment outcomes in patients with chronic nasal dysfunction.

Main Methods:

  • A retrospective analysis of 513 patients with chronic nasal dysfunction who completed the DyNaChron questionnaire between June 2016 and December 2021.
  • Patients were categorized into nasal polyposis (NP) or septo(rhino)plasty+inferior turbinoplasty (SPIT) surgical groups.
  • The standard error of measurement (SEM) method was employed to calculate MCIDs.

Main Results:

  • The MCID for the DyNaChron global score was 60 for NP and 58 for SPIT.
  • Symptom-specific MCIDs were determined for nasal obstruction, anterior and posterior rhinorrhea, and olfaction.
  • A significant proportion of patients demonstrated clinical improvement, with 91% in the NP group and 65% in the SPIT group.

Conclusions:

  • Established MCIDs for the DyNaChron questionnaire facilitate the interpretation of treatment response.
  • These MCIDs allow for both global and symptom-specific evaluations of chronic nasal dysfunction's impact on quality of life.
  • The findings support the use of DyNaChron MCIDs in clinical practice for individual patient and group assessments.