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Updated: Jul 13, 2025
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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
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Hydroxyapatite: A journey from biomaterials to advanced functional materials
Sudip Mondal1, Sumin Park2, Jaeyeop Choi3
1Digital Healthcare Research Center, Institute of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of Korea.
Advances in Colloid and Interface Science
|October 15, 2023
Summary
Hydroxyapatite (HAp) has evolved from a simple biocompatible material to a multifunctional advanced material. Its applications now extend beyond bone regeneration to drug delivery, biosensing, and even catalysis, driven by nanoengineering and surface modifications.
Area of Science:
- Biomaterials Science
- Materials Engineering
- Nanotechnology
Background:
- Hydroxyapatite (HAp) is a well-established biomaterial, primarily known for its biocompatibility and bioactivity.
- Historically, HAp has been extensively used in bone tissue engineering and dental applications due to its osteoconductive properties.
Purpose of the Study:
- To provide an overview of the advancements in Hydroxyapatite (HAp) materials.
- To highlight the transformation of HAp from a traditional biomaterial to a versatile functional material.
- To explore the expanding applications of HAp beyond biomedical fields.
Main Methods:
- Tailoring HAp composition, morphology, and surface characteristics through advanced synthesis and engineering.
- Incorporating functional ions and molecules into HAp for enhanced therapeutic properties.
- Developing nanostructured HAp materials for targeted applications.
Main Results:
- HAp exhibits enhanced mechanical strength, controlled drug release, and improved biodegradability.
- Functionalized HAp materials show promise in antimicrobial coatings, growth factor delivery, and catalysis.
- Nanostructured HAp offers potential for targeted drug delivery, imaging, and theranostics.
Conclusions:
- Hydroxyapatite (HAp) has evolved into a multifunctional material with diverse applications.
- Nanoengineering and surface modifications are key to unlocking HAp's advanced functionalities.
- HAp-based materials show significant potential in biomedicine, catalysis, sensing, and energy storage.
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