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Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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Syphilis-related Membranous Nephropathy in a 35-year-old Woman

Yuki Nakayama1, Masayuki Yamanouchi1, Hiroki Mizuno1

  • 1Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, Japan.

Internal Medicine (Tokyo, Japan)
|October 15, 2023
PubMed

Insights

Syphilis can cause membranous nephropathy (MN) with specific IgG deposits. Prompt antibiotic treatment resolved proteinuria in a patient with syphilis-associated MN, highlighting its importance in differential diagnosis.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Immunology

Background:

  • Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults.
  • Distinguishing primary MN from secondary causes is crucial for appropriate treatment.
  • Syphilis is a systemic infection that can affect multiple organs, including the kidneys.
Keywords:
Treponema pallidum hemagglutination testlupus nephritismembranous nephropathysyphilisthe serologic test for syphilis

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