Outcomes of endovascular treatment for popliteal artery disease
Arne M Müller1, Leoni Löhn-Kannengießer1, Christian Bradaric1
1Klinik und Poliklinik für Innere Medizin I., Klinikum rechts der Isar, Technische Universität München, Germany.
Insights
Endovascular therapy for popliteal artery disease shows high success. Balloon angioplasty alone is linked to better outcomes than stenting, which increases restenosis risk, especially in diabetic patients.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Peripheral Artery Disease Management
Background:
- Peripheral artery disease (PAD) management, particularly endovascular revascularization for popliteal artery lesions, presents significant challenges.
- Limited data exists on predictors for successful outcomes in these complex cases.
Purpose of the Study:
- To evaluate predictors of restenosis after endovascular treatment of popliteal artery lesions.
- To assess the outcomes of different endovascular strategies for femoropopliteal disease.
Main Methods:
- Retrospective analysis of 227 endovascular procedures in 197 patients with popliteal artery lesions.
- Primary endpoint: hemodynamically relevant restenosis.
- Follow-up duration: median of 10 months.
Main Results:
- High technical success rate (98%) for endovascular procedures.
- Overall restenosis rate was 23% at median 10-month follow-up.
- Stent implantation (36.0% vs. 19.1%) and diabetes (HR 2.0) significantly predicted restenosis.
Conclusions:
- Endovascular therapy for popliteal artery disease offers high technical success and promising mid-term outcomes.
- Balloon angioplasty alone may be preferable to stenting to reduce restenosis risk.
- Diabetes and stent use are key predictors for restenosis in popliteal artery interventions.
Abstract:
Background: Finding the appropriate endovascular revascularization strategy for patients with peripheral artery disease and a popliteal artery lesion remains particulary challenging. Data regarding predictors for a beneficial outcome are scarce. Patients and methods: All endovascular procedures of popliteal artery lesions (n=227) performed in 197 patients between February 2009 and May 2018 at our institution were retrospectively analyzed. Hemodynamically relevant restenosis represented the primary endpoint. Results: The overall technical success rate was 98% and yielded 99% for stenoses (n=145) and 97% for occlusions (n=82). In a median follow-up of 10 months, the overall rate of restenosis was 23%. After 1 and 2 years, the primary patency rates were 76% and 55% and the secondary patency rate was 100%, respectively. The estimated probability of restenosis was significantly higher in stented lesions (stent vs. no stent; 36.0% vs. 19.1%; p=0.030). Multivariate analysis identified stent implantation (hazard ratio: 2.4; overall P=0.010) and diabetes (hazard ratio 2.0; P=0.023) as significant predictors for the development of restenosis. Conclusions: Endovascular therapy for popliteal artery disease was associated with high technical success rates and accompanied with a promising mid-term outcome, particularly in lesions treated with balloon angioplasty alone.
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Sites for measruring blood pressure
The Brachial Artery: Primary Site for Blood Pressure Measurement
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care


