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Related Experiment Video

Updated: Jul 13, 2025

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

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Smart alginate inks for tissue engineering applications.

Mozhgan Keshavarz1,2, Mohammadjavad Jahanshahi3, Masoud Hasany4

  • 1Department of Materials Science and Engineering, Faculty of Engineering & Technology, Tarbiat Modares University, P. O. Box: 14115-143, Tehran, Iran.

Materials Today. Bio
|October 16, 2023
PubMed
Summary

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This summary is machine-generated.

Scalable alginate bioinks are crucial for advancing 3D and 4D bioprinting. These "dry" state materials enable the creation of dynamic tissue constructs for tissue engineering and regenerative medicine.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Significant progress in tissue engineering has not yet yielded fully functional human organs.
  • Challenges in replicating native tissue complexity hinder clinical translation.
  • Bioprinting offers solutions, but dynamic, adaptable constructs are needed, leading to 4D bioprinting.

Purpose of the Study:

  • To review the design of scalable alginate bioinks for 3D and 4D bioprinting in a "dry"/air state.
  • To highlight alginate's role in overcoming limitations in bioprinting ink technology.
  • To explore applications beyond tissue engineering, including soft robotics and bioelectronics.

Main Methods:

  • Review of current research on alginate bioink design for 3D and 4D bioprinting.
Keywords:
3D bioprinting4D bioprintingBioprintingHydrogelsTissue engineering

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  • Focus on "dry"/air state printing methodologies.
  • Analysis of alginate's properties supporting scalability and versatility.

    • Main Results:

    • Alginate demonstrates exceptional properties, scalability, and versatility for bioprinting.
    • Alginate bioinks are key to developing dynamic, shape-evolving tissue constructs.
    • The development of "dry" state alginate bioinks facilitates easier printing and scalability.

    Conclusions:

    • Scalable alginate bioinks are essential for the advancement of 3D and 4D bioprinting.
    • These materials are pivotal for creating complex tissue constructs in tissue engineering and regenerative medicine.
    • Alginate-based bioinks hold potential for emerging fields like soft robotics and bioelectronics.