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CRISPR-Cas9 delivery strategies with engineered extracellular vesicles

Yaoyao Lu1, Kelly Godbout1, Gabriel Lamothe1

  • 1Centre de Recherche du CHU de Québec -Université Laval, Québec city, QC G1V4G2, Canada.

Molecular Therapy. Nucleic Acids
|October 16, 2023
PubMed
Summary

Extracellular vesicles (EVs) show promise for delivering CRISPR-Cas9 gene editing tools. This review explores methods to enhance EV loading and targeting for effective genetic disease therapies.

Keywords:
CRISPR-Cas9MT: Exploiting Extracellular Vesicles as Therapeutic Agents Special Issuedeliveryextracellular vesiclesgene therapytissue targeting

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