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Updated: Jul 13, 2025

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
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Published on: September 5, 2011

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The Anaphylactoid Syndrome of Pregnancy: Two Autopsy Cases

Ioannis Plantzas1, Athina Tousia1, Dimitrios Vlachodimitropoulos1

  • 1Forensic Medicine and Toxicology, National and Kapodistrian University of Athens, Athens, GRC.

Cureus
|October 16, 2023
PubMed

The anaphylactoid syndrome of pregnancy (ASP) is a rare emergency with significant mortality and morbidity, in which the amniotic fluid and fetal cells enter the maternal circulation leading to respiratory failure, altered mental status, hypotension, and disseminated intravascular coagulation. The term ASP was recently introduced to replace the term amniotic fluid embolism since the clinical manifestations of the entity were more similar to a septic or anaphylactic shock rather than that of an embolic event. Two autopsy cases are described, regarding a 35-year-old gravida 2 para 1 and a 34-year-old gravida 1 para 0, where the cause of death was determined to be ASP.

Keywords:
amniotic fluid embolismanaphylactoid syndrome of pregnancyautopsydeathdiffuse intravascular coagulationfetuslungs

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