Stevens-Johnson Syndrome in a Patient With Recent SARS-CoV-2 Infection and Ciprofloxacin Administration

Area of Science:

• Dermatology
• Infectious Diseases
• Pharmacology

Background:

• Stevens-Johnson syndrome (SJS) is a rare, severe mucocutaneous reaction with high morbidity and mortality.
• It is often triggered by medications or infections in genetically susceptible individuals.
• SJS involves blistering skin, mucosal erosions, and systemic symptoms, potentially progressing to epidermal necrolysis.

Observation:

• A case study of a female patient presenting with SJS is detailed.
• The patient had a recent SARS-CoV-2 infection.
• Ciprofloxacin administration followed the SARS-CoV-2 infection.

Findings:

• The patient developed Stevens-Johnson syndrome.
• The SJS was secondary to both SARS-CoV-2 infection and ciprofloxacin treatment.
• This case illustrates a rare dual etiology for SJS.

Implications:

• Highlights the potential for SARS-CoV-2 infection to precipitate SJS.
• Underscores the importance of considering drug reactions, like ciprofloxacin-induced SJS, post-infection.
• Emphasizes the need for vigilance in diagnosing and managing SJS, especially with complex triggers.