A highly-detailed anatomical study of left atrial auricle as revealed by in-vivo computed tomography

Cesare Mantini1, Francesco Corradi2, Fabrizio Ricci1,3

  • 1Department of Neuroscience, Imaging and Clinical Sciences, "G. D'Annunzio" University, Chieti, Italy.

Heliyon
|October 16, 2023
PubMed

Insights

The left atrial appendage (LAA) frequently forms blood clots, increasing stroke risk. Its variable shape is key to understanding clot formation and atrial fibrillation origins.

Area of Science:

  • Cardiology
  • Radiology
  • Cardiac Surgery

Background:

  • The left atrial appendage (LAA) is a primary source of intracardiac thrombi, significantly contributing to stroke incidence.
  • The LAA is also a major origin site for atrial fibrillation in patients undergoing ablation.
  • LAA morphology exhibits high variability, with shape and structure influencing thrombus formation.

Purpose of the Study:

  • To review the normal anatomy of the LAA using various imaging techniques.
  • To emphasize the relationship between LAA morphology and thrombus formation.
  • To provide insights into LAA embryology.

Main Methods:

  • Review of imaging techniques including computed tomography (CT), magnetic resonance imaging (MRI), and echocardiography.
  • Analysis of LAA morphological characteristics.
  • Discussion of LAA embryological development.

Main Results:

  • Detailed description of normal LAA anatomy across different imaging modalities.
  • Correlation established between specific LAA morphological features and the propensity for thrombus development.
  • Embryological insights into LAA development.

Conclusions:

  • Understanding LAA anatomy and its morphological variations is critical for clinicians.
  • LAA morphology is a significant factor in thrombus formation and atrial fibrillation.
  • Advanced imaging techniques are essential for LAA assessment.

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