Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Continuous ambulatory peritoneal dialysis and bone.

J A Delmez, M D Fallon, M A Bergfeld

    Kidney International
    |September 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Phthalate exposure and pubertal development in a longitudinal study of US girls.

    Human reproduction (Oxford, England)·2014
    Same author

    The association between parental perception of neighborhood safety and asthma diagnosis in ethnic minority urban children.

    Journal of urban health : bulletin of the New York Academy of Medicine·2012
    Same author

    Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United States.

    Environmental research·2007
    Same author

    Interactions among GSTM1, GSTT1 and GSTP1 polymorphisms, cruciferous vegetable intake and breast cancer risk.

    Carcinogenesis·2007
    Same author

    ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer.

    British journal of cancer·2003
    Same author

    Tumour necrosis factor superfamily cytokines and the pathogenesis of inflammatory osteolysis.

    Annals of the rheumatic diseases·2002
    Same journal

    KDIGO Life Cycle of Guideline Development Series Part 6: Bridging the Gap between Guidelines and Clinical Practice: The KDIGO Approach to Global Implementation and Education in Nephrology.

    Kidney international·2026
    Same journal

    KDIGO Life Cycle of Guideline Development Series Part 5: Guideline updates and a living model for the future.

    Kidney international·2026
    Same journal

    Crystal-storing histiocytosis causing severe acute kidney injury.

    Kidney international·2026
    Same journal

    Peritoneal dialysis in a patient with extensive burn scarring.

    Kidney international·2026
    Same journal

    COPA syndrome unmasked by anti-neutrophil cytoplasmic antibody-positive immune-complex nephritis.

    Kidney international·2026
    Same journal

    Monitoring anti-nephrin antibodies in the management of recurrent diffuse podocytopathy.

    Kidney international·2026
    See all related articles

    Continuous ambulatory peritoneal dialysis (CAPD) improves bone health in uremic patients. This treatment enhances bone mineralization and reduces excess osteoid, benefiting the uremic skeleton.

    Area of Science:

    • Nephrology
    • Bone Histomorphometry
    • Mineral Metabolism

    Background:

    • Uremic bone disease is a common complication in patients with chronic kidney disease.
    • Histological assessment is crucial for understanding bone pathology in uremia.

    Purpose of the Study:

    • To investigate the impact of continuous ambulatory peritoneal dialysis (CAPD) on the histological features of uremic bone disease.
    • To evaluate changes in bone matrix deposition and mineralization after one year of CAPD therapy.

    Main Methods:

    • Bone biopsy was performed on twelve patients before and after one year of CAPD.
    • Histomorphometric analysis quantified osteoid volume, width, and surface.
    • Tetracycline labeling assessed mineralization lag time.

    Related Experiment Videos

    Main Results:

    • CAPD treatment led to a reduction in relative osteoid volume, mean osteoid seam width, and total osteoid surface.
    • Mineralization lag time was shortened, indicating enhanced matrix mineralization.
    • These improvements occurred independently of bone aluminum levels.

    Conclusions:

    • CAPD therapy enhances osteoblast mineralizing capacity in uremic patients.
    • Continuous ambulatory peritoneal dialysis is beneficial for improving the skeletal health of patients with uremic bone disease.