Related Experiment Video

Updated: Jul 13, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.1K

Incidence and risk factors of contrast-induced nephropathy in acute stroke patients undergoing computed tomography

Muhannad A Asiri1, Mohammed S Alqahtani1, Saeed A Alqahtani1

  • 1From the Neurology unit (Asiri, Alharbi, Aqeeli, Alzahrani, Alwadai), Department of Medicine, King Fahad hospital, Jeddah, from the Neurology unit (Alqahtani M), Department of Medicine, Armed Forces Hospital-Southern Region, Khamis Mushait, and from the Unit of Neurology (Alqahtani S), College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.

Neurosciences (Riyadh, Saudi Arabia)
|October 16, 2023
PubMed

Insights

Contrast-induced nephropathy (CIN) affects 8.2% of acute stroke patients undergoing CT angiography. Intracerebral hemorrhage and abnormal baseline creatinine significantly increase CIN risk, highlighting the need for careful patient management.

Area of Science:

  • Nephrology
  • Neurology
  • Radiology

Background:

  • Acute stroke management often involves contrast-enhanced imaging like Computed Tomography Angiography (CTA).
  • Contrast-induced nephropathy (CIN) is a potential complication following contrast administration.
  • Understanding CIN prevalence and risk factors in acute stroke patients is crucial for optimizing care.

Purpose of the Study:

  • To determine the incidence of CIN in acute stroke patients undergoing brain CTA.
  • To identify significant risk factors associated with CIN development in this population.

Main Methods:

  • Retrospective analysis of acute stroke patients at King Fahad Hospital, Jeddah, from March to November 2022.
  • Inclusion criteria: baseline creatinine, CTA within 24 hours of symptom onset, and follow-up creatinine within 5 days.
  • Data analysis focused on identifying correlations between patient characteristics and CIN development.

Main Results:

  • Out of 182 patients who underwent brain CTA, 8.24% developed CIN.
  • Intracerebral hemorrhage (ICH) was associated with a 7-fold increased risk of CIN (OR=6.7).
  • Abnormal baseline creatinine (OR=7.8) and hypertension (OR=2.1) significantly elevated CIN risk.

Conclusions:

  • The incidence of CIN in acute stroke patients undergoing CTA is 8.2%.
  • Key risk factors include ICH, abnormal baseline creatinine, and hypertension.
  • Vigilance in managing these patients is essential to mitigate CIN risk and ensure optimal clinical outcomes.
Abstract

More Related Videos

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens06:02

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

11.8K
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.3K

Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
12
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
22
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
14
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
253
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
30
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
19