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Uptake of pertussis immunization in pregnancy and determinants of vaccination in Toronto, Canada

James Wright1, Michelle Science2, Selma Osman3

  • 1Public Health Ontario, Toronto, Ontario, Canada.

Vaccine
|October 16, 2023
PubMed

Insights

Maternal pertussis vaccination uptake in Toronto increased from 2018-2020, but remains below desired levels. Vaccination rates were higher for those pregnant in more recent years and for mothers born in Canada.

Area of Science:

  • Public Health
  • Immunization
  • Maternal Health

Background:

  • Pertussis (whooping cough) poses significant risks to infants under six months.
  • Maternal pertussis vaccination during pregnancy is recommended in Canada to protect infants.
  • Data on vaccination coverage in Canada was lacking.

Purpose of the Study:

  • To evaluate the uptake of maternal pertussis vaccination in Toronto, Canada.
  • To identify factors associated with pertussis vaccination during pregnancy.

Main Methods:

  • Recruitment of mother-infant pairs at The Hospital for Sick Children, Toronto (2018-2020).
  • Logistic regression analysis to assess demographic associations with self-reported vaccination.

Main Results:

  • 31.3% (76/243) of mothers received pertussis vaccination during pregnancy.
  • Vaccination odds increased significantly with each year of pregnancy and for mothers born in Canada.

Conclusions:

  • Maternal pertussis vaccination uptake in Ontario has risen recently.
  • Coverage rates are still lower than optimal, indicating a need for further improvement.
Abstract

Keywords:
Immunization in pregnancyPertussisVaccine preventable diseases

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