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An Analysis of Laryngomalacia and Its Interplay With Obesity and Obstructive Sleep Apnea in Pediatric Inpatients

Dean G Kennedy1, Nicholas R Wilson1, Amos Mwaura1

  • 1Otolaryngology - Head and Neck Surgery, Boston University School of Medicine, Boston, USA.

Cureus
|October 17, 2023
PubMed

Insights

Childhood obesity significantly increases the risk of laryngomalacia, a condition affecting the voice box. Preventing obesity is crucial for reducing laryngomalacia and obstructive sleep apnea in children.

Area of Science:

  • Pediatrics
  • Otolaryngology
  • Public Health

Background:

  • Laryngomalacia is a common congenital condition affecting the larynx.
  • Obesity is a growing concern in pediatric populations.
  • Obstructive sleep apnea (OSA) is frequently associated with upper airway issues.

Purpose of the Study:

  • To examine the association between pediatric obesity and laryngomalacia.
  • To investigate the relationship between laryngomalacia, obesity, and obstructive sleep apnea (OSA).

Main Methods:

  • Analysis of the 2016 Kids' Inpatient Database (KID), a subset of the Healthcare Cost and Utilization Project (HCUP).
  • Inclusion of neonatal admissions under three years old.
  • Statistical analysis of patient demographics, diagnoses, and hospital characteristics.

Main Results:

  • Obesity was associated with a 578.1% higher frequency of laryngomalacia.
  • Obstructive sleep apnea (OSA) showed a 5,243.2% increase in laryngomalacia frequency.
  • Combined obesity and laryngomalacia led to a 6,738.5% increase in OSA frequency.

Conclusions:

  • A significant correlation exists between pediatric obesity and an elevated risk of laryngomalacia.
  • Preventing childhood obesity is vital for mitigating laryngomalacia risk.
  • These findings aid in risk stratification for laryngomalacia and potential OSA development in children.

Keywords:
laryngomalaciaobesityobstructive sleep apneapediatric airwayrisk stratification

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