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Updated: Jul 13, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
[Vitamin D and COVID-19: a communication far from reality]
Alberto Donzelli1, Emilio Maestri2
1Fondazione "Allineare Sanità e Salute", Milano; adonzelli@ats-milano.it.
Abstract:
The intake of Vitamin D against COVID-19 has theoretical bases. In the 3-year period of the pandemic, hundreds of favorable observational studies and some small randomized controlled trials (RCTs) have been produced.However, to date, RCTs of larger size and quality have unfavorable results and do not support its use, neither in oral form at various doses nor as injection boluses nor in prophylaxis nor in treatment of COVID-19, not even in severe or critical cases, nor to prevent deaths.The results of a recent sequential meta-analysis of a few RCTs, presented as 'definitive evidence', are biased by the weight of the improper inclusion of an observational study.Interference with correct information, both in the media and in scientific communication, risks obscuring in clinical practice the conclusions of the most valid studies available.
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