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[Melatonin-Mediated Inhibitory Effect on Hyperimmune Status of Acquired Aplastic Anemia]

Meng-Ying Gao1, Mei-Li Ge2, Jia-Li Huo1

  • 1Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin 300020, China.

Zhongguo Shi Yan Xue Ye Xue Za Zhi
|October 17, 2023
PubMed
Summary

Aplastic anemia (AA) patients have lower melatonin levels, impacting immune function. Melatonin supplementation in vitro suppressed T cell activation and proliferation in AA patients, suggesting a therapeutic role.

Keywords:
T cellsaplastic anemiaimmunoregulationmelatonin

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