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Updated: Jul 13, 2025

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Natural Extracts for Antibacterial Applications.

Cuihong Chen^1,2,3, Lin Chen^1,2,3, Congyang Mao¹

¹Biomedical Materials Engineering Research Center, Hubei Key Laboratory of Polymer Materials, Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, School of Materials Science & Engineering, State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei University, Wuhan, 430062, China.

Small (Weinheim an Der Bergstrasse, Germany)

|October 17, 2023

Summary

This summary is machine-generated.

Natural extracts from plants, animals, and microbes offer promising antibacterial solutions against drug-resistant bacteria. This review explores their mechanisms and future potential in combating infectious diseases.

Keywords:

antibacterial biocompatibility biodegradability natural extracts safety

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Area of Science:

Microbiology
Natural Product Chemistry
Pharmacology

Background:

Bacterial infections and epidemics pose significant global health threats.
Increasing antibiotic resistance necessitates novel therapeutic strategies.
Natural extracts offer biocompatible alternatives to synthetic antimicrobials.

Purpose of the Study:

To review recent advancements in antibacterial natural extracts.
To explore extracts from plant, animal, and microbial sources.
To discuss their antibacterial mechanisms and future applications.

Main Methods:

Literature review of scientific databases.
Analysis of studies on natural extracts' antibacterial properties.
Synthesis of information on synergistic antibacterial approaches.

Main Results:

Natural extracts exhibit significant antibacterial activity.
Diverse mechanisms of action are employed by these extracts.
Synergistic strategies enhance the efficacy of natural antimicrobials.

Conclusions:

Natural extracts represent a viable frontier for developing new antibacterial agents.
Further research into mechanisms and synergistic combinations is warranted.
These natural compounds hold promise for combating multidrug-resistant bacteria.