Related Experiment Video

Updated: Jul 13, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.5K

Clinical Profiles and One-Year Outcome in Middle Eastern Patients With Atrial Fibrillation and Hypertension: Analysis

Abdullah Al-Kasasbeh1, Ahmad Abdalmajeed Alghzawi2,3, Mohamad Jarrah1

  • 1Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Angiology
|October 18, 2023
PubMed

Insights

Hypertension significantly worsens outcomes for atrial fibrillation patients in the Middle East. Patients with both conditions experienced higher rates of stroke, heart attack, and major bleeding events over one year.

Area of Science:

  • Cardiology
  • Clinical Research
  • Public Health

Background:

  • Limited data exists on hypertension's impact on atrial fibrillation outcomes in the Middle East.
  • Hypertension is a common comorbidity in patients with atrial fibrillation.

Purpose of the Study:

  • To assess the effect of coexisting hypertension on clinical profiles.
  • To evaluate the 1-year prognosis of Middle Eastern patients with atrial fibrillation and hypertension.

Main Methods:

  • A multicenter, prospective cohort study involving 1849 non-valvular atrial fibrillation patients.
  • Patients were followed for 1 year, with outcomes compared between those with and without hypertension.
  • Data collected included clinical features, medication use, and adverse events.

Main Results:

  • 76.4% of atrial fibrillation patients had hypertension, with higher rates of comorbidities like diabetes and coronary heart disease.
  • Hypertension was associated with increased risks of stroke, systemic embolism, acute coronary syndrome, and major bleeding.
  • Atrial fibrillation patients with hypertension showed significantly higher rates of stroke/systemic embolism (4.5%), ACS (2.4%), and rehospitalization (27.9%) at 1 year.

Conclusions:

  • Coexisting hypertension is linked to a worse baseline clinical profile in Middle Eastern atrial fibrillation patients.
  • Hypertension significantly increases the risk of adverse cardiovascular events and major bleeding in this population.
  • These findings highlight the importance of managing hypertension in atrial fibrillation patients for improved prognosis.

Keywords:
atrial fibrillationhypertensionmiddle eastern populationoral anticoagulantsprognosisstroke

More Related Videos

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.7K
The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

83.7K

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
15
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
14
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
12
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
14
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
22
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
9