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A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit

Christopher S Waters1, Sigurd B Angenent2, Steven J Altschuler1

  • 1Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell Reports
|October 18, 2023
PubMed

Keywords:
CP: Molecular biologyPINK1Parkincircuitdelaymathematical modelmitophagy decisionquantitative microscopysynthetic biologysystems biologythreshold

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