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TCR-Sequencing Provides a Barcode of Immune Activation and Target Organ Damage in Human Hypertension

Sara Perrotta1, Daniela Carnevale1,2

  • 1Department of Angiocardioneurology and Translational Medicine, Unit of Neuro and Cardiovascular Physiology, Italy (S.P., D.C.).

Hypertension (Dallas, Tex. : 1979)
|October 18, 2023
PubMed
Abstract

No abstract available in PubMed .

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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