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Related Experiment Video

Updated: Jul 13, 2025

Influenza Virus Propagation in Embryonated Chicken Eggs

Influenza Virus Propagation in Embryonated Chicken Eggs

Published on: March 19, 2015

Many potential pathways to future pandemic influenza.

David M Morens¹, Jaekeun Park², Jeffery K Taubenberger³

¹Office of the Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Science Translational Medicine

|October 18, 2023

Summary

This summary is machine-generated.

Predicting future influenza A pandemics remains challenging due to limited understanding and resources. While H5N1 avian influenza is a concern, other viral strains also pose pandemic risks.

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Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses

Published on: January 15, 2020

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Last Updated: Jul 13, 2025

Influenza Virus Propagation in Embryonated Chicken Eggs

Influenza Virus Propagation in Embryonated Chicken Eggs

Published on: March 19, 2015

Influenza A Virus Studies in a Mouse Model of Infection

Influenza A Virus Studies in a Mouse Model of Infection

Published on: September 7, 2017

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses

Published on: January 15, 2020

Area of Science:

Virology
Epidemiology
Public Health

Background:

Influenza A viruses have historically caused pandemics.
Current scientific understanding and resources limit the ability to predict future pandemics.
Avian influenza H5N1 has been a significant concern since 1997.

Purpose of the Study:

To highlight the challenges in predicting influenza A pandemics.
To underscore the potential for various influenza A strains to cause pandemics.
To emphasize the need for enhanced preparedness beyond specific strains like H5N1.

Main Methods:

Review of historical pandemic data.
Analysis of current virological surveillance.
Assessment of pandemic preparedness strategies.

Main Results:

Future influenza A pandemics cannot be accurately predicted.
Multiple influenza A subtypes possess pandemic potential.
Pandemic risk extends beyond the well-documented H5N1 strain.

Conclusions:

Enhanced global surveillance and research are crucial for pandemic preparedness.
A broader approach is needed to address the diverse threats of influenza A viruses.
Proactive strategies are essential to mitigate the impact of unpredictable influenza pandemics.