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Updated: Jul 13, 2025
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Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
Published on: January 29, 2014
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Auditory central pathways in children and adolescents with multiple sclerosis
Dayane Aparecida Nascimento Barbosa1, Liliane Aparecida Fagundes Silva1, Alessandra Giannella Samelli1
1Universidade de São Paulo, Faculdade de Medicina, Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo SP, Brazil.
Arquivos De Neuro-Psiquiatria
|October 18, 2023
Summary
Children and adolescents with multiple sclerosis (MS) show abnormal auditory evoked potentials, indicating delayed neural conduction and processing deficits. These findings highlight the impact of MS on the central auditory pathway in young individuals.
Area of Science:
- Neuroscience
- Pediatrics
- Audiology
Background:
- Multiple sclerosis (MS) is an inflammatory demyelinating disease affecting the central nervous system.
- Auditory evoked potential studies indicate neural processing deficits in adults with MS.
- Electrophysiological responses in pediatric MS patients remain understudied.
Purpose of the Study:
- To evaluate the central auditory pathway in children and adolescents with MS.
- Utilize brainstem auditory evoked potentials (BAEP) and long-latency auditory evoked potentials (LLAEP).
Main Methods:
- Study included 17 pediatric MS patients (9-18 years) and 17 healthy controls.
- All participants had normal hearing and no middle ear issues.
- Assessed using click-BAEP and LLAEP with oddball paradigm and tone-burst stimuli.
Main Results:
- Abnormal electrophysiologic responses were found in 60% of MS patients.
- BAEP revealed delayed wave V latency and prolonged interpeak latencies (III-V, I-V) in MS patients.
- LLAEP showed abnormal responses in 52.94% of MS patients, with generally longer latencies and smaller amplitudes.
Conclusions:
- Pediatric MS patients exhibit abnormal BAEP, suggesting delayed neural conduction.
- Abnormal LLAEP results indicate reduced neural processing speed and auditory sensory discrimination.
- These findings underscore auditory pathway dysfunction in young individuals with MS.
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