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Published on: June 9, 2021
Rhabdomyolysis in McArdle disease caused by scuba diving
Ulysse George McCann1, Thomas Park2
1Hospital Medicine, University of Florida College of Medicine, Gainesville, Florida, USA umccann@ufl.edu.
Abstract:
McArdle disease is a glycogen storage disease that results in rhabdomyolysis during intense exercise. A number of different triggers have been described. We evaluated a patient with McArdle disease who presented with rhabdomyolysis after recreational scuba diving. There was no concern for barotrauma or decompression sickness. His symptoms resolved with standard-of-care management for non-diving-related rhabdomyolysis. Features of his experience provoked questions about the diving-related factors contributing to his presentation. We present the case and explore possible mechanisms of diving-related injury in patients with McArdle disease, including the possible effects of hyperoxia, hyperbaria, hypothermia and strenuous activity.
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