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Updated: Jul 13, 2025

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Macromolecular condensation buffers intracellular water potential

Joseph L Watson1, Estere Seinkmane1, Christine T Styles2

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|October 18, 2023
PubMed
Summary

Cellular water potential is rapidly buffered by temperature and osmotic strength changes. Biomolecular condensation of proteins dynamically regulates water availability, protecting cells from environmental stress.

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