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Transventricular Endoscopic Approach for Cystic Craniopharyngioma: Case Series.
Akshay Kulkarni1, Subhas Konar2, Dhaval Shukla2
1Department of Neurosurgery, University of Illinois, Chicago, Illinois, United States.
Journal of Neurological Surgery. Part B, Skull Base
|October 19, 2023
Summary
Transventricular endoscopy offers a minimally invasive option for cystic craniopharyngiomas. This approach, involving endoscopic fenestration and reservoir placement, shows promise in managing these tumors with low morbidity.
Area of Science:
- Neurosurgery
- Oncology
- Minimally Invasive Procedures
Background:
- Craniopharyngioma treatment varies, with high morbidity associated with radical excision.
- Conservative approaches are increasingly favored for cystic craniopharyngiomas.
- Transventricular endoscopy presents a minimally invasive option for these tumors.
Purpose of the Study:
- To describe the authors' experience with transventricular endoscopy for cystic craniopharyngiomas.
- To evaluate the efficacy and safety of endoscopic fenestration and reservoir placement.
- To assess outcomes in patients with third ventricle cystic craniopharyngiomas.
Main Methods:
- Retrospective review of patients with cystic craniopharyngiomas.
- Management involved transcortical transventricular endoscopic biopsy and catheter/reservoir placement.
- Patients with hydrocephalus were treated with fenestration and aspiration or reservoir placement.
Main Results:
- Twenty-nine patients with cystic craniopharyngiomas and hydrocephalus were treated.
- No morbidity was associated with the endoscopic procedure.
- Recurrence occurred in 27.5% of cases, managed with reaspiration, resection, or shunting.
Conclusions:
- Neuroendoscopic fenestration, aspiration, and catheter reservoir placement is a viable treatment option.
- This technique is suitable for cystic craniopharyngiomas extending into the third ventricle with hydrocephalus.
- The procedure, followed by radiation, offers an alternative to more invasive treatments.

