[Significance of diskography and contrast medium/enzyme interaction]

The introduction and routine usage of nucleolysis in treatment of lumbar disc disease has led to recognition of the importance of discography. In addition to confirmation and documentation of needle placement, discography is useful for diagnosis and exclusion of contraindications to nucleolysis such as escape of enzyme to nerve sheath or vascular system. Gross leakage of radiopaque material indicates probable communication to nervous structures. Possible interaction of enzyme and radiopaque were examined.