Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Properties of Organometallic Compounds01:23

Properties of Organometallic Compounds

1.0K
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tuning enantioselective drug adsorption in isoreticular homochiral metal-peptide frameworks through proximity pore interactions.

Journal of materials chemistry. B·2025
Same author

Aqueous-stable Mn(II)-MOF nanoparticles with high <i>r</i><sub>1</sub> relaxivity and biocompatibility: a novel <i>T</i><sub>1</sub> MRI contrast agent.

Journal of materials chemistry. B·2025
Same author

Stacked, twisted, and porous: structural diversity in photoactive porphyrin-based metal-organic frameworks.

Chemical communications (Cambridge, England)·2025
Same author

Uncapping energy transfer pathways in metal-organic frameworks through heterogeneous structures.

Nature communications·2025
Same author

The contrasting impacts of polyethylene glycol on electrochemical behaviors of Fe and Zn metal anodes in aqueous batteries.

Chemical communications (Cambridge, England)·2025
Same author

The Temperature Dependence of the Langmuir Adsorption Model for a Single-Site Metal-Organic Framework.

Langmuir : the ACS journal of surfaces and colloids·2025

Related Experiment Video

Updated: Jul 12, 2025

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange
04:51

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange

Published on: June 23, 2023

2.9K

Multivariate metal-organic frameworks generated through post-synthetic modification: impact and future directions.

Kyle T Smith1, Kyriakos C Stylianou1

  • 1Materials Discovery Laboratory (MaD Lab), Department of Chemistry, Oregon State University, 153 Gilbert Hall, OR 97331, Corvallis, Oregon, USA. kyriakos.stylianou@oregonstate.edu.

Dalton Transactions (Cambridge, England : 2003)
|October 19, 2023
PubMed
Summary

Multivariate (MTV) metal-organic frameworks (MOFs) overcome synthesis limitations by incorporating multiple components. Post-synthetic modification (PSM) enables enhanced MTV-MOF properties, even with incompatible functionalities.

More Related Videos

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.2K
Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

2.8K

Related Experiment Videos

Last Updated: Jul 12, 2025

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange
04:51

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange

Published on: June 23, 2023

2.9K
Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.2K
Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

2.8K

Area of Science:

  • Materials Science
  • Chemistry
  • Nanotechnology

Background:

  • Reticular chemistry, exemplified by metal-organic frameworks (MOFs), covalent-organic frameworks (COFs), and metal-organic polyhedra (MOPs), offers structural versatility and tailored porosity.
  • Traditional MOF synthesis often relies on de novo conditions, limiting structures to single ligands and metals.

Purpose of the Study:

  • To explore strategies for generating multivariate (MTV) MOF structures with enhanced properties.
  • To investigate the potential of post-synthetic modification (PSM) for creating MTV-MOFs.

Main Methods:

  • Development of strategies for synthesizing MTV-MOFs incorporating multiple ligands or metals.
  • Application of post-synthetic modification (PSM) to introduce new functionalities into pre-synthesized MOFs.

Main Results:

  • MTV-MOFs demonstrate enhanced properties due to the incorporation of additional functionalities.
  • PSM allows for the successful introduction of new functionalities, even those incompatible with initial MOF synthesis conditions.
  • This approach expands the design space for advanced MOF materials.

Conclusions:

  • Multivariate MOFs offer a route to overcome limitations in traditional MOF synthesis.
  • Post-synthetic modification is a viable strategy for creating functionalized MTV-MOFs with tailored properties.
  • MTV-MOFs hold significant potential for diverse applications requiring advanced material characteristics.