Analysis of Risk Factors for Complications after Percutaneous Coronary Intervention in Patients with Acute ST-segment
Insights
Multiple pre-existing diseases and elevated hs-CRP, NT-proBNP, HbA1c, and Scr levels are key risk factors for post-percutaneous coronary intervention (PCI) complications in acute ST-segment elevation myocardial infarction (ASTEMI) patients.
Area of Science:
- Cardiology
- Internal Medicine
- Medical Research
Background:
- Acute ST-segment elevation myocardial infarction (ASTEMI) is a severe form of myocardial infarction.
- Percutaneous coronary intervention (PCI) is the primary treatment for ASTEMI.
- Post-PCI complications pose significant risks to patient health and survival.
Purpose of the Study:
- To identify risk factors for complications in ASTEMI patients undergoing PCI.
- To analyze predictors of adverse outcomes following PCI for ASTEMI.
Main Methods:
- A cohort of 107 ASTEMI patients treated with PCI was studied.
- Patients were categorized into a safety group (no complications) and a risk group (with complications).
- Logistic regression analysis was employed to determine factors associated with post-PCI complications.
Main Results:
- No significant differences in sex, age, BMI, Killip classification, or infarct site were observed between groups.
- The risk group showed higher rates of multiple pre-existing diseases, reduced left ventricular ejection fraction (LVEF < 40%), and more coronary lesions.
- Elevated levels of hs-CRP, NT-proBNP, HbA1c, and serum creatinine (Scr) were significantly higher in the risk group.
Conclusions:
- Multiple pre-existing diseases, hs-CRP, NT-proBNP, HbA1c, and Scr are independent risk factors for post-PCI complications in ASTEMI.
- Monitoring these indicators can aid in preventing complications.
- These findings highlight crucial targets for risk stratification and management in ASTEMI patients post-PCI.
Background:
Acute ST segment elevation myocardial infarction (ASTEMI) is the most common and serious type of AMI, percutaneous coronary intervention (PCI) is currently the most commonly used approach for clinical treatment of ASTEMI. After PCI, patients with ASTEMI are very prone to various complications, which will seriously threaten their health and life safety.
Objective:
This study aims to analyze the risk factors for complications in patients with acute ST-segment elevation myocardial infarction (ASTEMI) treated with percutaneous coronary intervention (PCI).
Methods:
A total of 107 patients with ASTEMI who were subjected to PCI from October 2021 to December 2022 were selected as study subjects. Patients were divided into a safety group (no complications, n = 63) and a risk group (n = 45) based on the presence of postoperative complications. Baseline data (age, sex, etc.), Killip classification, left ventricular ejection fractions (LVEF), and routine blood test results were collected from patients in both groups for Logistic regression analysis to obtain relevant factors affecting the occurrence of post-PCI complications.
Results:
There were no differences between the safety group and the risk group in terms of sex, age, body mass index (BMI), Killip classification, and infarct site (P > .05). Compared with the safety group, the risk group exhibited a higher proportion of patients with multiple pre-existing diseases, LVEF < 40%, and number of coronary artery lesions ≥ 1, and higher levels of hs-CRP, NT-proBNP, HbA1c and Scr (P < .05). Logistic regression analysis results showed that multiple pre-existing diseases, hs-CRP, NT-proBNP, HbA1c, and Scr were relevant factors affecting the occurrence of post-PCI complications (P < .05).
Conclusion:
Multiple pre-existing diseases, hs-CRP, NT-proBNP, HbA1c, and Scr were all independent risk factors for the occurrence of post-PCI complications. Future clinical attention should be paid to these indicators in patients with ASTEMI in order to prevent post-PCI complications.
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