Related Experiment Video
Updated: Jul 12, 2025

Lipidomics and Transcriptomics in Neurological Diseases
Published on: March 18, 2022
Role of rafts in neurological disorders
U Meza1, C Romero-Méndez1, S Sánchez-Armáss1
1Departamento de Fisiología y Biofísica, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Introduction:
Rafts are protein-lipid structural nanodomains involved in efficient signal transduction and the modulation of physiological processes of the cell plasma membrane. Raft disruption in the nervous system has been associated with a wide range of disorders.
Development:
We review the concept of rafts, the nervous system processes in which they are involved, and their role in diseases such as Parkinson's disease, Alzheimer disease, and Huntington disease.
Conclusions:
Based on the available evidence, preservation and/or reconstitution of rafts is a promising treatment strategy for a wide range of neurological disorders.
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