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Updated: Jul 12, 2025

Use of 3D Robotic Ultrasound for In Vivo Analysis of Mouse Kidneys
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Segmentation of kidney mass using AgDenseU-Net 2.5D model.

Peng Sun1, Zengnan Mo2, Fangrong Hu1

  • 1School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, China.

Computers in Biology and Medicine
|October 20, 2023
PubMed
Summary

This study introduces a resource-efficient two-step deep learning method for segmenting kidneys, tumors, and cysts in CT scans. The AgDenseU-Net model achieves high accuracy, offering a valuable tool for kidney mass assessment.

Keywords:
2.5D modelAgDenseU-NetAutomatic down-sampling of 3D imagesKiTS21Kidney tumor segmentationMedical image segmentation

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Urology

Background:

  • The Kidney and Kidney Tumor Segmentation Challenge 2021 (KiTS21) dataset aids research in kidney mass segmentation.
  • Accurate segmentation of kidneys, tumors, and cysts is crucial for assessing kidney mass complexity and aggressiveness.
  • Traditional 3D deep learning models require significant computational resources.

Purpose of the Study:

  • To propose a computationally efficient method for segmenting kidneys, tumors, and cysts.
  • To evaluate the performance of the proposed method on the KiTS21 dataset.
  • To provide a reference for kidney tumor segmentation techniques.

Main Methods:

  • A two-step approach involving automatic down-sampling of 3D CT images to reduce volume while preserving features.
  • Fine segmentation using the AgDenseU-Net (Attention gate DenseU-Net) 2.5D model.
  • Evaluation using Hierarchical Evaluation Classes (HECs) specific to KiTS21, alongside standard metrics.

Main Results:

  • The AgDenseU-Net model achieved high Dice scores on the KiTS21 dataset: 0.971 for kidney, 0.883 for kidney mass, and 0.815 for tumor.
  • Without HECs, the model obtained Dice scores of 0.950 for kidney, 0.878 for tumor, and 0.746 for cyst.
  • The proposed method demonstrates effectiveness in segmenting kidney, tumor, and cyst components.

Conclusions:

  • The proposed two-step deep learning scheme significantly reduces computational resource requirements for kidney mass segmentation.
  • The AgDenseU-Net model shows promising results for accurate segmentation of kidneys, tumors, and cysts.
  • This method serves as a valuable reference for future kidney tumor segmentation research and clinical applications.