Related Experiment Video
Updated: Jul 12, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
Respiratory physiotherapy as a tool to allow and optimize lung donation
Ricardo Miguel Rodrigues-Gomes1,2, Lucas Lage Cendón2, Rosa Martínez Rolán1,2
1Facultade Medicina, Universidade de Santiago de Compostela, Santiago Compostela, Spain.
Respiratory physiotherapy can improve lung viability in potential organ donors by clearing secretions. This case study shows how ventilator techniques successfully increased oxygenation, enabling lung transplantation.
Area of Science:
- Medicine
- Pulmonology
- Transplantation
Background:
- Lung donation is critical for patients with end-stage lung disease.
- Secretion retention can impede lung viability and donor suitability.
- The PaO2/FiO2 ratio is a key indicator of lung oxygenation capacity.
Observation:
- A potential lung donor presented with a low PaO2/FiO2 ratio, initially disqualifying them.
- A respiratory physiotherapist employed ventilator-based techniques to manage secretions.
- Significant secretion removal was achieved, leading to improved oxygenation.
Findings:
- The patient's PaO2/FiO2 ratio increased substantially after the intervention.
- This improvement allowed the patient to be accepted as a potential lung donor.
- Successful lung extraction and transplantation were performed.
Implications:
- Respiratory physiotherapy may play a vital role in optimizing lung donors.
- These techniques could increase the pool of viable lungs for transplantation.
- This approach offers a potential solution to overcome secretion-related barriers in lung donation.
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