Related Experiment Video
Updated: Jul 12, 2025

Production of Nanofibrillar Patterned Collagen for Tissue Engineering
Published on: September 20, 2024
Collagen a1(XI) structure prediction by Alphafold 2
Abu Sayeed Chowdhury1, Julia Thom Oxford2
1Biomolecular Sciences Graduate Program, Center of Biomedical Research Excellence, Boise State University, Boise, Idaho USA.
Abstract:
Collagen α1(XI) is a minor fibrillar collagen involved in the critical regulation of collagen fibrils such as nucleation, assembly, and regulation of fibril diameter. The amino propeptide domain of the collagen α1(XI) is retained on the surface of the collagen fibril for an extended period of time and may play a crucial role in the interaction with extracellular matrix glycosaminoglycans and other proteins during the process of fibrillogenesis. Understanding the mechanism of action of this protein will ultimately help us understand the organization and assembly of the extracellular matrix that underlies the structural integrity of connective tissues.
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