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Lymphoma-related intussusception in children: diagnostic challenges and clinical characteristics

Rensen Zhang1,2, Minjie Zhang1, Ruyu Deng1

  • 1Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.

European Journal of Pediatrics
|October 20, 2023
PubMed

Insights

Lymphoma-related intussusception in children often presents in older males with prolonged pain. Ultrasound findings like enlarged lymph nodes can aid early detection, guiding timely surgical intervention for better outcomes.

Area of Science:

  • Pediatric Gastroenterology
  • Pediatric Oncology
  • Abdominal Imaging

Background:

  • Intussusception in children can be caused by various conditions, including lymphoma, making early diagnosis crucial for effective treatment.
  • Identifying the precise cause of intussusception is often challenging and time-consuming, necessitating advanced diagnostic strategies.

Purpose of the Study:

  • To investigate the clinical and imaging characteristics of lymphoma-related intussusception in pediatric patients.
  • To improve the early detection and management of intussusception caused by intestinal lymphoma in children.

Main Methods:

  • A retrospective review of pediatric patients admitted between 2012 and 2023 with intussusception secondary to intestinal lymphoma.
  • Analysis of demographic, clinical, and imaging data, comparing lymphoma-related cases with non-lymphoma-related intussusception.

Main Results:

  • The study identified 31 children with lymphoma-related intussusception, who were older (median 87 months) and predominantly male compared to non-lymphoma cases.
  • Patients with lymphoma-related intussusception presented with prolonged abdominal pain, and ultrasound revealed mesenteric lymph node enlargement and intra-abdominal masses.
  • Enema reduction success rates were lower in the lymphoma-related group, highlighting the complexity of diagnosis and management.

Conclusions:

  • Swift identification of lymphoma-related intussusception, characterized by specific clinical and ultrasound findings, is vital for prompt intervention.
  • Age, persistent symptoms, and characteristic ultrasound findings should raise suspicion for lymphoma-related intussusception in children.
  • Timely surgical intervention guided by preoperative imaging is essential for accurate diagnosis and effective management.

Keywords:
ChildrenDiagnosisIntussusceptionLymphomaSurgical intervention

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