Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Nonideal Two-Component Liquid Solutions

Nonideal Two-Component Liquid Solutions

Nonideal liquid solutions, also known as real solutions, do not strictly follow Raoult's law. Raoult's law is a rule of thumb in physical chemistry. However, not all mixtures adhere to this law due to varying molecular interactions. For example, in an acetone/chloroform solution, the individual vapor pressures of the components are lower than expected, resulting in a total vapor pressure below that predicted by Raoult's law, causing a negative deviation.On the other hand, in an ethanol/water...

Characteristics of Fluids

Characteristics of Fluids

Fluids differ from solids primarily in their molecular structure and stress response. Solids have tightly packed molecules with strong intermolecular forces, maintaining their shape and resisting deformation. In contrast, fluids have molecules spaced farther apart with weaker forces, allowing them to flow and deform easily.
Fluids, which include both liquids and gases, are substances that deform continuously under shearing stress. For example, water and oil are liquids with molecules that can...

Reynolds Transport Theorem

Reynolds Transport Theorem

The Reynolds transport theorem provides a framework to relate the time rate of change of an extensive property within a system to that in a control volume, which is crucial for analyzing fluid dynamics. Extensive properties, such as mass, velocity, acceleration, temperature, and momentum, can be expressed in terms of the mass of a fluid portion. These properties are called extensive because they depend on the system's size, while intensive properties are their corresponding values per unit mass.

Typical Model Studies

Typical Model Studies

Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.

Turbulent Flow

Turbulent Flow

Turbulent flow is characterized by unpredictable fluctuations in velocity and pressure, which result in a chaotic fluid movement distinct from the orderly patterns of laminar flow. While laminar flow is governed by smooth, parallel layers with minimal mixing, turbulent flow exhibits highly irregular, three-dimensional patterns. This behavior arises due to instabilities in the fluid's velocity profile, and amplifies as the flow velocity increases. Minor disturbances, known as turbulent spots,...

Turbulent Flow: Problem Solving

Turbulent Flow: Problem Solving

Carbonation is a process used to dissolve carbon dioxide gas in a liquid, commonly used in the production of carbonated beverages. Achieving efficient carbonation requires careful control of temperature, pressure, and flow conditions. By adjusting these parameters, carbonation efficiency can be maximized, producing a higher concentration of CO2 in the liquid.
Temperature is a key factor in CO2 solubility. In this case, the CO2 gas and the liquid are cooled to 20°C. Lower temperatures enhance...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Novel Ultrafast Sample-to-Answer Microfluidic Platform for Highly Sensitive On-Site Quantification of Avian Influenza Virus.

Analytical chemistry·2026

Same author

Air trap and removal on a pressure driven PDMS-based microfluidic device.

The Review of scientific instruments·2024

Same author

Laser-induced selective wax reflow for paper-based microfluidics.

RSC advances·2022

Same author

Fabrication of Transparent and Flexible Digital Microfluidics Devices.

Micromachines·2022

Same author

Assessment of microplastics using microfluidic approach.

Environmental geochemistry and health·2022

Same author

CO<sub>2</sub> laser fabrication of hydrogel-based open-channel microfluidic devices.

Biomedical microdevices·2021

Search research articles

Related Experiment Video

Updated: Jul 19, 2026

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices

Published on: November 1, 2007

Reversible bonding of microfluidics: Review and applications.

Y Zhang¹, K Sun¹, Y Xie²

¹School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing, People's Republic of China.

The Review of Scientific Instruments

|October 20, 2023

Summary

Reversible bonding methods are crucial for microfluidic chip fabrication, enabling chip reuse and content retrieval. This review highlights recent advancements and applications in this essential area of microfluidics.

More Related Videos

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

Related Experiment Videos

Last Updated: Jul 19, 2026

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices

Non-plasma Bonding of PDMS for Inexpensive Fabrication of Microfluidic Devices

Published on: November 1, 2007

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

Area of Science:

Microfluidics
Materials Science
Chemical Engineering

Background:

Microfluidic chip fabrication relies heavily on bonding techniques to create enclosed channels.
Conventional bonding methods are often irreversible, risking damage during chip disassembly.
Reversible bonding is increasingly necessary for applications requiring chip reuse or sample recovery.

Purpose of the Study:

To review recent developments in reversible bonding methods for microfluidic devices.
To discuss the applications of these novel reversible bonding techniques.
To provide insights into the future outlook of reversible bonding in microfluidics.

Main Methods:

Literature review of recent advancements in microfluidic reversible bonding.
Analysis of various reversible bonding techniques and their mechanisms.
Compilation of current and potential applications utilizing reversible bonding.

Main Results:

Identification of emerging reversible bonding strategies in microfluidics.
Demonstration of diverse applications enabled by reversible bonding, such as reusable diagnostic devices.
Discussion of the advantages and limitations of different reversible bonding approaches.

Conclusions:

Reversible bonding is a critical enabling technology for advanced microfluidic applications.
Continued innovation in reversible bonding methods will expand the capabilities of microfluidic systems.
The field is moving towards more sustainable and versatile microfluidic device fabrication.