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Congenital syphilis and perinatal mortality.

D M Judge, N Tafari, R L Naeye

    Pediatric Pathology
    |January 1, 1986
    PubMed
    Summary

    Congenital syphilis contributes to 6% of perinatal mortality in Addis Ababa. Risk factors include unwanted pregnancies and lack of antenatal care, with recognizable effects even in stillborns.

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    Area of Science:

    • Obstetrics and Gynecology
    • Pediatrics
    • Infectious Diseases

    Background:

    • Congenital syphilis is a significant contributor to perinatal mortality in Addis Ababa, Ethiopia.
    • Approximately 6% of perinatal deaths in the region are linked to this preventable infection.

    Purpose of the Study:

    • To investigate the prevalence and risk factors of congenital syphilis.
    • To describe the pathological findings and clinical associations of congenital syphilis in stillborn infants.

    Main Methods:

    • Retrospective analysis of 65 autopsies performed on stillborn infants.
    • Review of accompanying maternal examinations and interviews to identify risk factors.

    Main Results:

    • Congenital syphilis was identified as a key factor in perinatal mortality.
    • Identified risk factors include unwanted pregnancies, previous stillbirths, multiple sexual partners, and absence of antenatal care.
    • Pathological findings include enlarged liver, spleen, and placenta, premature labor, and recognizable signs even in macerated stillborns.

    Conclusions:

    • Congenital syphilis is a significant and recognizable cause of perinatal death in Addis Ababa.
    • Addressing risk factors such as unwanted pregnancies and improving access to antenatal care are crucial for prevention.

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