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Alterations in Blood Pressure01:30

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Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
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Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Hypertension I: Introduction01:28

Hypertension I: Introduction

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Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
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Hypertension II: Pathophysiology01:29

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Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
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Disorders of the Autonomic Nervous System01:18

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
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Does COVID-19 Cause Non-Dıpper Hypertension?

Fatih Sivri1, Ismail Türköz2, Mehtap Şencan2

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COVID-19 significantly disrupts blood pressure regulation in hypertensive patients, leading to a higher prevalence of non-dipper hypertension post-infection. This study highlights altered circadian blood pressure patterns after COVID-19 recovery.

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Hypertension Research

Background:

  • Coronavirus disease 2019 (COVID-19) is a global health concern.
  • Hypertension management is crucial, with circadian blood pressure patterns playing a key role.
  • The long-term cardiovascular impact of COVID-19, particularly on blood pressure regulation, requires further investigation.

Purpose of the Study:

  • To investigate the impact of COVID-19 on blood pressure (BP) circadian patterns.
  • To determine the prevalence of new-onset non-dipper hypertension in patients post-COVID-19.
  • To compare post-COVID-19 BP patterns in hypertensive patients with a control group.

Main Methods:

  • Prospective, single-center study involving 722 patients hospitalized with COVID-19.
  • Ambulatory blood pressure (ABP) monitoring during hospitalization and 1 month post-discharge.
  • Comparison of ABP data with a control group of healthy hypertensive individuals without COVID-19.

Main Results:

  • 187 COVID-19 patients and 136 controls were included after exclusions.
  • Post-COVID-19 patients exhibited significantly higher mean 24-hour, nighttime, and daytime diastolic BP.
  • New-onset non-dipper hypertension was significantly more prevalent in the COVID-19 group.

Conclusions:

  • COVID-19 significantly disturbs the circadian blood pressure pattern in patients with pre-existing hypertension.
  • A non-dipper hypertension pattern frequently develops in the post-COVID-19 period.
  • These findings underscore the importance of monitoring BP circadian rhythms in hypertension management after COVID-19 infection.