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Does COVID-19 Cause Non-Dıpper Hypertension?
Fatih Sivri1, Ismail Türköz2, Mehtap Şencan2
1Aydin Nazilli State Hospital, Nazilli, Turkey.
Insights
COVID-19 significantly disrupts blood pressure regulation in hypertensive patients, leading to a higher prevalence of non-dipper hypertension post-infection. This study highlights altered circadian blood pressure patterns after COVID-19 recovery.
Area of Science:
- Cardiology
- Infectious Diseases
- Hypertension Research
Background:
- Coronavirus disease 2019 (COVID-19) is a global health concern.
- Hypertension management is crucial, with circadian blood pressure patterns playing a key role.
- The long-term cardiovascular impact of COVID-19, particularly on blood pressure regulation, requires further investigation.
Purpose of the Study:
- To investigate the impact of COVID-19 on blood pressure (BP) circadian patterns.
- To determine the prevalence of new-onset non-dipper hypertension in patients post-COVID-19.
- To compare post-COVID-19 BP patterns in hypertensive patients with a control group.
Main Methods:
- Prospective, single-center study involving 722 patients hospitalized with COVID-19.
- Ambulatory blood pressure (ABP) monitoring during hospitalization and 1 month post-discharge.
- Comparison of ABP data with a control group of healthy hypertensive individuals without COVID-19.
Main Results:
- 187 COVID-19 patients and 136 controls were included after exclusions.
- Post-COVID-19 patients exhibited significantly higher mean 24-hour, nighttime, and daytime diastolic BP.
- New-onset non-dipper hypertension was significantly more prevalent in the COVID-19 group.
Conclusions:
- COVID-19 significantly disturbs the circadian blood pressure pattern in patients with pre-existing hypertension.
- A non-dipper hypertension pattern frequently develops in the post-COVID-19 period.
- These findings underscore the importance of monitoring BP circadian rhythms in hypertension management after COVID-19 infection.
Abstract:
Coronavirus disease 2019 (COVID-19) remains a health problem worldwide. The present study aimed to investigate the effect of blood pressure (BP) on the circadian pattern and prevalence of new-onset non-dipper hypertension in the post-COVID period in patients with known hypertension. This prospective single-center study included 722 patients hospitalized for COVID-19 infection. Ambulatory BP (ABP) data were collected during their initial hospitalization. The ABP data were reassessed 1 month after the patients were discharged. The results were compared with a healthy control group with known hypertension but without COVID-19 infection. After exclusion criteria were applied, the study included 187 patients with COVID-19 and 136 healthy hypertensive controls. Post-COVID ABP showed that patients with COVID-19 had significantly higher mean 24-h systolic and diastolic BP, mean nighttime systolic and diastolic BP, and mean daytime diastolic BP than the control group. In addition, new-onset non-dipper hypertension was significantly higher in patients with COVID-19. This study demonstrated for the first time that the circadian pattern is disturbed and a non-dipper pattern develops in individuals with known hypertension during the post-COVID period.
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