Coronary Artery Calcium Identified on Non-Gated Chest CT Scans: A Wasted Opportunity for Preventive Cardiological

Beatriz Valente Silva1, Miguel Nobre Menezes1, Rui Plácido1

  • 1Cardiology Department, Centro Hospitalar Universitário Lisboa Norte, CAML, CCUL, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Heart, Lung & Circulation
|October 22, 2023
PubMed

Insights

Coronary artery calcium (CAC) on standard chest CT predicts cardiovascular events and mortality. Early detection of CAC on chest CT aids risk stratification, but underreporting is common.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Preventive Cardiology

Background:

  • Coronary artery calcium (CAC) on cardiac CT predicts cardiovascular events.
  • Standard chest CT may detect CAC, offering a potential screening opportunity.

Purpose of the Study:

  • Evaluate CAC on non-gated chest CT against coronary angiography (CAG).
  • Assess CAC's impact on cardiovascular outcomes and mortality.

Main Methods:

  • Retrospective analysis of 114 patients with prior chest CT and CAG.
  • Quantitative (Agatston score) and qualitative CAC assessment on non-gated chest CT.

Main Results:

  • Moderate/severe CAC on chest CT predicted significant coronary lesions (OR 22) and mortality (OR 4).
  • Quantitative CAC predicted significant lesions (AUC 0.81).
  • Significant CAC detected in 80% of chest CTs, but only 25% were reported.

Conclusions:

  • CAC assessment on chest CT is feasible and correlates with coronary disease severity and mortality.
  • Chest CT offers a chance for cardiovascular risk stratification, though underreporting is prevalent.
Abstract

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