Related Experiment Video
Updated: Jul 12, 2025

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
Blood transfusions in non-major burns patients
Ioana Țichil1, Ioana Codruta Rus2, Diana Cenariu3
1University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania; Emergency County Hospital, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania; Department of Haematology "Ion Chiricuta" Institute of Oncology, 34-36 Republicii Street, Cluj-Napoca 400015, Romania.
Comorbidities in patients with non-major burn injuries increase the risk of anemia and blood transfusions. Understanding these risk factors can improve patient care and guide transfusion decisions.
Area of Science:
- Burn injury management
- Hematology
- Transfusion medicine
Background:
- Anemia is common in burn patients, often necessitating blood transfusions.
- Even minor burn injuries (< 20% Total Body Surface Area) can lead to anemia requiring transfusion.
- Understanding transfusion risk factors is crucial for improving care due to associated morbidity and mortality.
Purpose of the Study:
- Identify risk factors for blood product transfusion in non-major burn injury patients.
- Assess transfusion practices and their impact on patient outcomes.
- Inform clinical decisions for better patient management.
Main Methods:
- Retrospective analysis of 182 adult patients with non-major burn injuries (< 20% TBSA).
- Collected data on patient demographics, burn characteristics, comorbidities (Charlson index), and laboratory values (Hb).
- Analyzed outcomes including blood transfusions, wound infections, and length of hospital stay.
Main Results:
- 37.9% of patients developed anemia; 7.7% received blood transfusions.
- Transfused patients were older, had higher %TBSA burns, and greater comorbidity burden.
- Transfused patients with comorbidities experienced more wound infections and longer hospital stays.
Conclusions:
- Patient comorbidities are significant predictors of higher transfusion rates in non-major burn injuries.
- Transfusion decisions should align with current guidelines and individual patient needs due to transfusion risks.
- Tailoring transfusion strategies based on risk factors can optimize outcomes for burn patients.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

