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Updated: Jul 12, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
A method for cancer elemental risk assessments in hookah: An example in two common types of traditional and flavored
Lida Nikbakhtan1, Jalal Hassan2, Ali Pourshaban-Shahrestani2
1Department of Chemistry, South Tehran Branch, Islamic Azad University, Tehran, Iran.
Aim:
This study aimed to compare the elemental composition of traditional and flavored hookah tobacco, with a focus on heavy metals.
Methods:
We used inductively coupled plasma mass spectrometry (ICP-MS) to analyze the concentrations of 29 elements in the raw tobacco, tobacco ash, hookah water after smoking, and tobacco smoke.
Results:
The results showed that the traditional tobacco had significantly higher metal concentrations than the flavored tobacco in all samples. Most of the toxic metals (more than 98 %) remained in the smoke of both types of tobacco. The tobacco and hookah smoke contained high levels of harmful metals that can pose health risks to hookah users.•ICP-MS provides a comprehensive analysis of multiple elements simultaneously and it allows for precise quantification of metal concentrations in different samples.•ICP-MS requires specialized equipment and trained personnel and it may not detect elements present in extremely low concentrations.
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