Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

192
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
192
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

263
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
263
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

459
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
459
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

149
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
149
Histology of the Large Intestine01:26

Histology of the Large Intestine

886
The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
886
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

73
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
73

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical presentation and treatment of a case of anti-signal recognition particle-positive immune-mediated necrotizing myopathy.

Proceedings (Baylor University. Medical Center)·2026
Same author

A Rare Case of a Splenic Abscess as the Origin of Illness in Exudative Pleural Effusion.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2025
Same author

Bridging the Gap Between Inpatient and Outpatient Care.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2024
Same author

Close outpatient follow-up associated with reduced readmission rates in patients with inflammatory bowel disease.

Proceedings (Baylor University. Medical Center)·2024
Same author

The Impact of a Paracentesis Clinic on Internal Medicine Resident Procedural Competency.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2024
Same author

Nightmare on CIL Street: A Simulation Series to Increase Confidence and Skill in Responding to Clinical Emergencies.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2024

Related Experiment Video

Updated: Jul 12, 2025

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

9.5K

Gastrointestinal Bleeding Caused by Large Intestine Amyloidosis.

Nikhil Seth1, Victoria A Jaeger2, Namisha Thapa2

  • 1Central Texas Veterans Affairs Health Care System, Temple.

Federal Practitioner : for the Health Care Professionals of the VA, Dod, and PHS
|October 23, 2023
PubMed
Summary

Intestinal amyloidosis, a rare condition of abnormal protein folding, can cause gastrointestinal bleeding. Early diagnosis and multidisciplinary care are vital for managing this complex disorder.

More Related Videos

Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

67.3K
Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

402

Related Experiment Videos

Last Updated: Jul 12, 2025

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

9.5K
Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

67.3K
Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

402

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Pathology

Background:

  • Amyloidosis is a rare protein-folding disorder causing tissue dysfunction.
  • While amyloid deposition affects multiple organs, intestinal involvement is infrequent.

Observation:

  • A 79-year-old male presented with gastrointestinal bleeding and constitutional symptoms.
  • Symptoms included weight loss, nausea, difficulty swallowing, and fatigue.
  • Diagnostic procedures included esophagogastroduodenoscopy and colonoscopy.

Findings:

  • Biopsy confirmed intestinal amyloidosis as the cause of symptoms.
  • This case underscores the importance of considering amyloidosis in the differential diagnosis for GI bleeding.

Implications:

  • Highlights the need for a broad differential diagnosis in patients with gastrointestinal bleeding.
  • Emphasizes the importance of early identification and multidisciplinary management for optimal patient outcomes.
  • Tailored care plans are essential for patients diagnosed with intestinal amyloidosis.